Virus and Malware removal and prevention that we use and why
This is what we use in on a day to day bases, I make no claim as to if this is the best or not, we find this works 99% of the time for us.

Some background on the various tools.

1. Microsoft Security Essentials, this we have found to be almost unparalleled in finding those hard to find rootkits and malware that embed themselves deeply in the OS, make sense really after all Microsoft made the OS.
2. G-Date, ok let’s be honest not the first choice for ease of use at the business end, and takes a fair amount of resources, however, if you’re willing to put some effort in configuring and have a reasonable machine this is the best first-line defence we have come across, it’s a bit flaky with it AV updates and always has been so you need to make sure that both databases are updated without any issues.
3. Hitman Pro, we can’t take credit for this a client came in with some issues and did a song and dance about Hitman Pro as a second defence, so we gave it a try and was, to say the least impressed it is now part of our AV arsenal.
4. ClamWin has been around for some time it's very good as an offline/call on-demand scanner nice to have a second opinion.
5. Microsoft Safety Scanner, this is quite new to us and still very much in a test but so far all results indicate that this will join our AV arsenal.
6. Panda seems to be very good at spotting and removing malware generally and good as the second option to MSS above.

For SMB prevention we use:

• Microsoft Security Essentials
• G-Data for single-user ‘total care’ for network ‘G-Data Business suit’
• Hitman Pro

For Enterprise prevention we use:

• Microsoft Security Essentials
• Symantec or Sophos Enterprise  
• Webroot

For removal and checking we use:

• Microsoft Safety Scanner
• Hitman Pro
• Microsoft Security Essentials
• Clamwin
• Panda
• Webroot

There is plenty of information about all these products on their related sites I see no reason to duplicate the information here, so please do your due diligence and if you come across any good tools please let us know, we will test and if they make the grade we will add them here and to our AV arsenal.

If you want to know who is considered the best in the enterprise field look at the latest Gartner report: Magic Quadrant for Endpoint Protection Platforms.

It's easy to scaremonger however given today's hostile internet and lack of understanding of modern digital threats coupled with poor user practices, these treats are very real so the solutions should be too.